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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
4.55
Human Site:
S347
Identified Species:
7.69
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
S347
K
L
G
G
N
N
T
S
E
K
A
D
G
L
S
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
S347
K
L
G
G
N
N
T
S
E
K
A
D
G
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
N444
S
M
K
L
G
G
N
N
A
S
E
K
A
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
G341
D
E
T
I
K
R
R
G
S
N
M
D
K
K
E
Rat
Rattus norvegicus
NP_001099948
974
110023
F312
I
A
V
I
L
T
N
F
D
D
G
R
P
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
K302
K
Q
A
V
T
K
G
K
N
K
T
G
S
A
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
K337
G
C
P
L
P
T
E
K
T
K
Q
E
Q
Q
M
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
K327
K
Q
A
T
S
K
E
K
G
V
D
S
E
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
A395
I
K
P
V
Y
T
G
A
Q
G
M
A
T
F
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
N423
F
N
D
D
S
D
D
N
P
S
P
E
K
K
A
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
L217
D
G
E
F
V
N
V
L
T
N
Y
H
T
N
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
I299
T
L
T
L
L
S
L
I
A
F
D
R
Y
G
N
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
L208
S
I
Y
A
G
G
V
L
A
D
E
M
G
M
G
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
Q505
T
L
R
P
Y
Q
K
Q
S
L
Y
W
M
L
A
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
0
N.A.
6.6
6.6
N.A.
13.3
N.A.
6.6
13.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
13.3
N.A.
6.6
13.3
N.A.
13.3
N.A.
13.3
20
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
6.6
N.A.
N.A.
20
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
8
0
0
0
8
22
0
15
8
8
8
15
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
8
0
8
8
0
8
15
15
22
0
8
0
% D
% Glu:
0
8
8
0
0
0
15
0
15
0
15
15
8
8
8
% E
% Phe:
8
0
0
8
0
0
0
8
0
8
0
0
0
8
0
% F
% Gly:
8
8
15
15
15
15
15
8
8
8
8
8
22
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
15
8
0
15
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
29
8
8
0
8
15
8
22
0
29
0
8
15
15
0
% K
% Leu:
0
29
0
22
15
0
8
15
0
8
0
0
0
29
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
15
8
8
8
8
% M
% Asn:
0
8
0
0
15
22
15
15
8
15
0
0
0
8
15
% N
% Pro:
0
0
15
8
8
0
0
0
8
0
8
0
8
0
0
% P
% Gln:
0
15
0
0
0
8
0
8
8
0
8
0
8
8
0
% Q
% Arg:
0
0
8
0
0
8
8
0
0
0
0
15
0
0
15
% R
% Ser:
15
0
0
0
15
8
0
15
15
15
0
8
8
0
22
% S
% Thr:
15
0
15
8
8
22
15
0
15
0
8
0
15
0
0
% T
% Val:
0
0
8
15
8
0
15
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
8
0
15
0
0
0
0
0
15
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _